Searchable abstracts of presentations at key conferences in endocrinology

ea0094oc2.5 | Endocrine Cancer and Late Effects | SFEBES2023

Androgen mediated metabolic perturbation in endocrine resistant breast cancer

Agbana Stephanie , Bleach Rachel , Allessi Dario , O'Reilly Michael W. , McIlroy Marie

Introduction: Although breast cancer (BC) is considered a treatable disease, >30% of patients with hormone receptor positive tumours will suffer recurrence post endocrine therapy. One of the fundamental features of cancer cells is their ability to modulate cell metabolism to facilitate survival, stress response, and proliferation. Increasing evidence suggests that these mechanisms play key roles in the development of treatment resistance. Recent publicatio...